Silofast 4 mg
Silofast 8 mg
Silofast is used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. Silofast relieves the symptoms of urinary retention caused by restricted urine flow as the prostate becomes enlarged and presses against the urethra (urine outlet tube from the bladder). This helps urine to flow more easily, prevents urine backlog in the bladder, restores bladder control and relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine. Silofast helps improve urine flow and reduce symptoms, which may reduce the need for surgery.
Silofast contains Silodosin, an alpha1-blocker (also known as alpha-adrenergic antagonist), that binds selectively and with high affinity to the alpha adrenergic receptor in smooth muscle of the prostate gland. Binding of Silodosin in Silofast blocks the action of naturally occurring adrenergic chemicals like noradrenaline which causes smooth muscle cells to contract and tighten. Benign prostatic hyperplasia (BPH) is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells. Silodosin relaxes these muscle cells which relieves the pressure exerted by the enlarged prostate gland on the urethra (urine outlet tube from the bladder) and also causes muscle cells in the neck of the bladder to relax.
The action of Silodosin removes the blockage to urine flow caused by the prostate gland and allows urine to flow more freely through the urethra; it also relaxes the bladder neck, allowing urine to pass out of the bladder more easily. Silofast is formulated for modified release, which means that the rate of absorption of the active ingredient Silodosin into your blood is controlled and you need only take one capsule a day.
Side effects include: dizziness, headache, abnormal ejaculation, asthenia (weakness), postural hypotension (dizziness on standing) and palpitations.
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